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The Particle Articles

David Exline


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Comparison of Raman and FTIR Spectroscopy: Advantages and Limitations

[fa icon="calendar'] Oct 9, 2013 9:55:10 AM / by David Exline posted in Blog, Featured Articles, Fourier transform infrared spectroscopy, FTIR spectroscopy, Raman spectroscopy

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Raman spectroscopy is an inelastic scattering phenomenon the probes molecular vibrations to provide a molecular fingerprint of materials. Currently, there are six major types of Raman spectroscopy in use today, which are: Spontaneous Raman Spectroscopy, Resonance Raman spectroscopy (RRS), Surface Enhanced Raman spectroscopy (SERS), Coherent Anti-Stokes Raman Scattering (CARS), Stimulated Raman Spectroscopy (SRS) and Spatially Offset Raman Spectroscopy (SORS).

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When Do You Bring in a Consultant?

[fa icon="calendar'] Apr 19, 2013 10:35:50 AM / by David Exline posted in Blog, Consultant Services

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The consultant is a valuable tool for any organization if properly utilized.  The key to gaining the most benefit to using a consultant starts with the need.  The need must be clearly identified as a one time need or ongoing need.  The organization must first determine if the appropriate expertise is represented within the organization.  If the specific expertise is present in house, then one must ask if outside help can add value to existing group.  Often times for specific problems, a consultant may be the right approach.

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David Exline, President

[fa icon="calendar'] Jan 29, 2013 9:50:34 AM / by David Exline posted in analytical instrumentation, analytical testing, Authors, Blog, chemical imaging, crime scene investigation, fluorescence microscopy, forensic expert, FTIR, GMP, hyperspectral imaging, light microscopy, pharmaceutical, pharmaceutical forensics, Raman chemical imaging, Raman spectroscopy, spectroscopy, trace evidence, USP testing methods

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David Exline
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Helping Generic Manufacturers Prove Bioequivalence of Suspension Nasal Sprays

[fa icon="calendar'] Apr 20, 2012 10:30:45 AM / by David Exline posted in analytical testing, aqueous suspension formulations, bioequivalence, Blog, critical path opportunities, FDA, in vitro, in vivo, Nasal Drug Products, Nasal suspension PSD, Pharmaceutical, pharmaceutical, pharmaceutical formulation, suspension nasal sprays

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In 2004, the FDA launched the Critical Path Initiative as a national strategy to drive innovation in development, evaluation and manufacturing of medical products1.  As part of this initiative, the FDA identified a number of Critical Path Opportunities (CPOs) for generic drugs.  Namely the CPO for Bioequivalence of Nasal Sprays, which identifies a need for direct measurement of particle size equivalence in suspension nasal sprays2.

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Gateway Analytical Scientists Take Part in the Pine-Richland School District STEAM Curriculum

[fa icon="calendar'] Apr 10, 2012 2:51:19 PM / by David Exline posted in Blog, Community, community, community support, education, forensics, Pine-Richland

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Two Gateway Analytical scientists (David Exline and Ryan Priore) have volunteered to take part in the advisory committee for the Science, Technology, Engineering, Arts, and Mathematics (STEAM) program in the Pine Richland School District.   The intention of this committee is to combine the talents and interests of the community to best support students within the Pine-Richland School District.  This group will meet periodically to discuss our focus on STEAM at both the elementary and secondary grade levels within the school district.  Discussions during our advisory committee meetings will focus on corporate outreach and partnerships, building student interest in STEAM education and future careers, and hands-on classroom applications of STEAM curriculum.

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Webinar Recap: Forensic Analysis of Hair and Fibers for Police and Attorneys

[fa icon="calendar'] Mar 19, 2012 9:30:13 AM / by David Exline posted in Blog, crime scene investigation, fibers collection methods, forensic fiber analysis, forensic hair analysis, Forensics, forensics, hair collection methods, trace evidence, Trace Evidence

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Webinar Recap: Forensic Gunshot Residue (GSR) Analysis for Police & Attorneys

[fa icon="calendar'] Mar 2, 2012 11:00:39 AM / by David Exline posted in Blog, crime scene investigation, forensic expert, Forensics, forensics, GSR analysis, gunshot residue analysis, trace evidence, Trace Evidence

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On Feb 7th, 2012 Gateway Analytical hosted a live webinar titled “Forensic Gunshot Residue Analysis for Police & Attorneys”. During the webinar our presenters, David Exline and Cara Plese, discussed what gunshot residue (GSR) is, how to collect it and control contamination, the historical and current methods of analytical testing of GSR, as well as a discussion on how terminology in the GSR community has changed and why.

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